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Retatrutide isn’t just appetite suppression it hits multiple metabolic pathways
It acts on GLP-1 GIP and glucagon receptors which is a big shift from older drugs
Fat loss isn’t only from eating less energy expenditure may increase too
Glucagon activity can raise metabolic rate unlike typical GLP-1s
It may improve how the body partitions nutrients not just reduce calories
Blood sugar control improves which indirectly supports fat loss.
Some users report feeling warmer hinting at thermogenic effects
Muscle preservation seems better compared to basic dieting
Appetite suppression is strong but not the whole story
Biggest takeaway it’s not just eating less it’s how the body responds differently